Medik8’s new PDRN and exosome serum is doctor-approved
The fountain of youth might not be real, but the science behind Medik8‘s latest skin care launch is.
The British brand used by stars like Rosie Huntington-Whiteley and Hailey Bieber recently rolled out an advanced serum that promises to target multiple signs of aging — yet is so gentle, it can even be used post-procedure.
The new Exo-PDRN Primastic+ Youthful Vitality Serum visibly improves radiance, tone and overall skin vitality using the buzziest of clinically-backed ingredients, like a proprietary exosome complex and a vegan version of PDRN, which is typically derived from salmon sperm DNA.
Promising clinical-grade results, the Exo-PDRN Primastic+ Serum counters redness while strengthening the skin barrier and improving the look of wrinkles and sagging, all while imparting luminosity. (The before-and-after pics are impressive.)
With all the buzz around these trendy ingredients, we asked Manhattan-based Dr. Jennifer Levine for her professional perspective.
“PDRN and exosomes represent the next frontier in cellular skin rejuvenation,” the double board-certified facial plastic surgeon told Page Six Style.
“PDRN acts as a powerful biostimulator that triggers DNA repair and aggressively cuts down inflammation,” according to the anti-aging expert — making it a great choice for post-procedure, and for countering redness.
Likewise, the NYC doc shared that the exosomes deliver a concentrated cocktail “directly to cells to accelerate collagen production. Together, they reset the cellular aging clock — making them a game changer for rapid healing and long-term tissue restoration.” (Well, we’re adding to cart after this!)
On the Medik8 website, Exo-PDRN Primastic+ Serum has a near-perfect rating with nearly 1,200 reviews already.
“I’ve only been using Exo-PDRN for a week, and my skin already looks different — smoother and more radiant,” reads one.
“After several weeks of use, my skin looked brighter, smoother, and more resilient, with a noticeable improvement in overall radiance,” echoed another customer.
Scroll on to shop a few more best sellers from the brand, including Huntington-Whiteley’s go-to r-Retinoate Day & Night.
Why Trust Page Six Style Shopping
This article was written by Erica Radol, Page Six Commerce Reporter. From identifying the top anti-aging skincare secrets the stars trust to dishing on the latest fashion collabs to finding a great deal on all of the above, Erica has a knack for reporting on – and even testing – Hollywood’s bestselling fashion and beauty products. Before joining Page Six in 2025, she wrote about entertainment, lifestyle and shopping trends for Us Weekly, The Daily Beast, Entertainment Tonight, Well+Good and Hearst.
