Eric Dane, Grey’s Anatomy and Euphoria Star, Dead at 53 –

Eric Dane, Grey’s Anatomy and Euphoria Star, Dead at 53 –

Actor dies nearly one year after announcing ALS diagnosis

A heartbreaking loss

February 20, 2026 – Eric Dane, best known for his roles on Grey’s Anatomy and Euphoria, has died at the age of 53, nearly one year after publicly revealing his diagnosis with ALS. News of his passing has sent shockwaves through the entertainment industry and among fans who followed his career for more than two decades.
A life cut short.

Eric Dane on 'Euphoria' in 2019. Eddy Chen/HBO

Image Credit: Eddy Chen/HBO

A career defined by impact

Dane rose to prominence as Dr. Mark Sloan on Grey’s Anatomy, becoming a fan favorite for his charisma and emotional depth. In later years, he earned renewed acclaim for his role as Cal Jacobs on Euphoria, showcasing a darker, more complex side of his acting range.
Roles remembered.

Jessica Biel (left) and Eric Dane in 2010's 'Valentine's Day' Ron Batzdorff/New Line Cinema

Image Credit: Ron Batzdorff/New Line Cinema

His ALS announcement

In early 2025, Dane shared that he had been diagnosed with amyotrophic lateral sclerosis, a progressive neurological disease. At the time, he spoke candidly about the challenges ahead while expressing gratitude for his family, colleagues, and supporters as he navigated life with the condition.
A brave disclosure.

Eric Dane spotted on rare family outing with wife Rebecca Gayheart

Image Credit: VEGAN / BACKGRID

Tributes pour in

Following his death, tributes from co-stars, fans, and industry figures have highlighted Dane’s talent, generosity, and resilience. Many praised not only his performances, but also his courage in facing illness publicly while continuing to work when possible.
An outpouring of grief.

Eric Dane in a wheelchair with Rebecca Gayheart and daughter Georgia.

Image Credit: BackGrid

Final thoughts

Eric Dane leaves behind a legacy marked by unforgettable characters and quiet strength. His passing is a reminder of both the fragility of life and the lasting power of storytelling through performance.

FAQs

Q1: How old was Eric Dane when he died?
He was 53 years old.

Q2: What illness was he battling?
Eric Dane had been diagnosed with ALS.

Q3: When did he announce his diagnosis?
He publicly shared his ALS diagnosis in early 2025.

Q4: What roles is he best known for?
He is best known for Grey’s Anatomy and Euphoria.

Q5: How is he being remembered?
As a talented actor and a resilient figure who faced illness with honesty and grace.

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